Environmental diseases is what you'll indeed see in the future. Having to stay hot in cold biomes and cold in hot biomes, yup. That's planned. Go play 7 Days to Die and you'll get a basic idea of where Rising World is going. You'll catch as cold, and etc from the environment that you'll have to worry about quite a lot with medicine being of high importance for when you survive.
How detailed is to be seen, yet wouldn't be surprised if we would see diseases naturally in swamp to ward off. Hogweeds themselves you'll have to be well protected in long sleeves so you wouldn't get skin irritation in the game.
There's a lot planned. You can see small signs of such in the winter type biomes when your character exhales. That in itself.......As for collapses in mines, I'd say leave that for Medieval Engineer as things might get a bit too tedious. Maybe some falling debris here and there, I guess, which would force you to wear a mining helmet and such for safety to negate damage.
Ohh neat! I have noticed the breathing bits which had me thinking! I actually own 7 Days to Die, but I haven't played it in over a year. Mostly cause zombies scare me terribly...
As for the mines, I considered mentioning cave ins, however, I was more or less thinking of poisonous gasses and or maybe even air depletion in places too far from the surface. Though that would be an issue with the undegeons underground so this is not really that important.